Figure 6

Oral administration of fidarestat increased the percentage of FoxP3⁺ Tregs in the spleen-derived CD4⁺CD25⁺ T cells population following RWE-challenge. The spleen-derived CD4⁺CD25⁺ T-cells from different groups were stained with FoxP3 antibodies and subjected to FACS analysis. The bars represent (A) CD25⁺FoxP3⁺ and (B) CD4⁺FoxP3⁺ population, data expressed as mean±SD (n = 5), *p<0.05 vs. RWE; **p<0.01 vs. RWE. RWE, ragweed pollen extract, Fida, fidarestat.