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Table 5 Correlation analysis on the levels of IL-17A and the percentage of Foxp3+Tregs in CD4+ T cells in the peripheral blood of COPD by SFC therapy

From: Relationship between the anti-inflammatory properties of salmeterol/fluticasone and the expression of CD4+CD25+Foxp3+regulatory T cells in COPD

 

Baseline

SFC therapy

Alteration

r1

r2

r3

IL-17A (ng/ml)

1.06 ± 0.06

0.95 ± 0.06

-0.11

   

Foxp3+Tregs (%)

3.33 ± 0.23

4.14 ± 0.21

0.81

-0.783***

-0.475*

-0.492*

  1. r1 = -0.783, ***p < 0.001, levels of IL-17A vs. Foxp3+ Tregs before SFC therapy (Baseline)
  2. r2 = -0.475, * p < 0.05, levels of IL-17A vs. Foxp3+Tregs after SFC therapy
  3. r3 = -0.492, * p < 0.05, alteration of IL-17A vs. Foxp3+Tregs in COPD by SFC therapy