Table 2 Reversal of MCT-Induced PAH by VIP, Bosentan, or Their Combination

24.3 ± 2.4

61.4 ± 4.8

33 ± 0.5

39 ± 1.2

26.0 ± 1.2

< 0.05

< 0.05

< 0.05

0.76 ± 0.07

3.9 ± 0.51

1.68 ± 0.19

1.76 ± 0.19

0.79 ± 0.05

< 0.05

< 0.05

< 0.05

0.26 ± 0.01

0.51 ± 0.03

0.47 ± 0.07

0.34 ± 0.02

NS

NS

< 0.05

0.20 ± 0.17

3.0 ± 0.26

0.3 ± 0.21

1.2 ± 0.28

0.3 ± 0.33

< 0.05

< 0.05

< 0.05