Figure 4

Mast cell densities in alveolar parenchyma from never-smoking controls and patients with CF and IPF. Data are presented as mast cells per mm² lung tissue. The total mast cell densities (A) and densities of each subtype, MC_T (B) and MC_TC (C), are presented in regions of normal, inflammatory and fibrotic alveolar parenchyma in each disease. Data are expressed as scatter plots where horizontal lines denote median values. Statistical differences to never-smoking controls using Mann-Whitney where * denotes p < 0.05, ** < 0.01, and *** p < 0.001.