Skip to main content
Figure 5 | Respiratory Research

Figure 5

From: Conditional deletion of epithelial IKKβ impairs alveolar formation through apoptosis and decreased VEGF expression during early mouse lung morphogenesis

Figure 5

Epithelial deletion of IKKβ decreases alveolar type I and II cells numbers. (A, B) Immunohistochemistry for Nkx2.1 with quantification of Nkx2.1-positive cells in (C) at P7. (D) Real-time quantitative PCR confirming decreased expression of Nkx2.1 mRNA in double transgenic compared to control lungs. Immunofluorescence for SP-C (green channel) and T1α (red channel) in control (E) versus double transgenic lungs (F) with respective quantification (G, H) at P7. [10 × magnification; insets represent binary image of T1α-positive pixels; Data are expressed as Mean ± SEM, *p < 0.05 in C-D and G-H].

Back to article page

Respiratory Research

ISSN: 1465-993X

Contact us