Table 1 Baseline characteristics of the UPLIFT® study population according to quartiles of RoD in post-bronchodilator FEV1
Rate of decline quartile | ||||
|---|---|---|---|---|
Q1 (n = 1241) | Q2 (n = 1241) | Q3 (n = 1241) | Q4 (n = 1241) | |
Male (%) | 77 | 72 | 75 | 80 |
Age (years) | 65 ± 9 | 65 ± 8 | 64 ± 8 | 63 ± 9 |
Smoking history (%) | ||||
Ex-smoker | 73 | 76 | 71 | 63 |
Current smoker | 27 | 24 | 29 | 37 |
Duration of COPD (years) | 10 ± 8 | 10 ± 8 | 10 ± 8 | 9 ± 7 |
Inhaled respiratory drugs (%) | ||||
LABA | 61 | 60 | 62 | 58 |
ICS | 63 | 61 | 60 | 61 |
LABA + ICS | 50 | 48 | 49 | 47 |
Anticholinergic | 43 | 44 | 43 | 46 |
SGRQ total score (units) | 45 ± 18 | 45 ± 17 | 45 ± 17 | 46 ± 17 |