Figure 2
From: Attenuation of antigen-induced airway hyperresponsiveness and inflammation in CXCR3 knockout mice
Effect of CXCR3 on airway inflammation and mucous production. Mice were immunized and challenged with OVA. Lungs were analyzed by H&E staining, scored for histopathological changes in lung inflammation and thickened airway epithelium, and by periodic acid-Schiff-staining for mucous production as described in Materials and Methods. A-D, Representative photomicrographs of hematoxylin- & eosin and periodic acid-Schiff-stained lung tissues. E, Semiquantative analysis of histopathologic changes using a scoring method as described in Materials and Methods, n = 5 animals per group, *, p < 0.05.