Figure 7

Histological assessment of lung sections. Naïve mice were sensitized with PBS- or GC frass-pulsed BMDC from wild type or PAR-2-/- mice on day 0. Mice were challenged with PBS (40 μl) or GC frass (40 μg/40 μl) on day 14. On day 17, lungs were isolated and fixed in formalin. Periodic Acid Schiff (PAS) staining of sectioned lungs from mice exposed to PBS-pulsed wild type BMDCs (A) or GC frass-pulsed wild type BMDCs (B). PAR-2-/- BMDC exposed to PBS (C) or GC frass (D) are also shown. Representative slides are shown of sections from 4-6 mice per group.