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Figure 5 | Respiratory Research

Figure 5

From: Increased oxidative stress and severe arterial remodeling induced by permanent high-flow challenge in experimental pulmonary hypertension

Figure 5

Immunohistochemical findings in pulmonary arteries and arterioles from experimental PH models. A: pulmonary arteriole of a MCT-treated animal; perivascular cells are staining with anti-malonedialdehyd antibody. B: Nitrotyrosin-staining in lungs from a MCT/PE-rat; endothelial cells within a remodeled pulmonary artery show pronounced staining. C: Pulmonary artery in an MCT-treated animal: in addition to the endothelial staining, smooth-muscle cells of the tunica media show are, to a lesser extent, nitrotyrosine-positive. D: IL-6 staining reveals positive endothelial cells in a small pulmonary artery of MCT/PE-treated animals. E: perivascular inflammatory cells express CCL5 (RANTES), F: and CX3CL1 (fractalkine) in MCT- and MCT/PE-animals.

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Respiratory Research

ISSN: 1465-993X

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