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Figure 4 | Respiratory Research

Figure 4

From: Altered surfactant homeostasis and recurrent respiratory failure secondary to TTF-1 nuclear targeting defect

Figure 4

TTF-1 expression. Lung tissue immunolabeled with anti-TTF-1 antibody (green) and nuclear labelling (Hoechst 33342, blue), confocal microscopy. a-b: TTF-1 expression in normal lung is confined to nuclear districts. c-d: TTF-1 protein distribution in patient's lung is markedly decreased in alveolar type II cell nuclei (c) and predominantly confined in their cytoplasm. Magnification bar: 20 μm.

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