Figure 3From: Altered surfactant homeostasis and recurrent respiratory failure secondary to TTF-1 nuclear targeting defectSurfactant-related protein expression. Confocal microscopy of lung biopsies from control (a, c, e, g) and patient (b, d, f, h), immunolabeled with antibodies against ABCA3 (a-b), pro SP-B (c-d), SP-B (e-f), pro SP-C (g-h) antibodies. ABCA3 labeling showed a faint and homogeneous reduction in the type II cell population in patient compared to control, whereas pro SP-B, SP-B and pro SP-C protein expression was similar. Magnification bar: 20 μm.Back to article page