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Figure 2 | Respiratory Research

Figure 2

From: Altered surfactant homeostasis and recurrent respiratory failure secondary to TTF-1 nuclear targeting defect

Figure 2

Alveolar type II cell ultrastructure. Transmission electron microscopy of lung tissue. A. normal lung tissue of a 5 month-old infant obtained from lobectomy for congenital cystic adenoid malformation showing a type II cell with numerous lamellar bodies filled with concentric pseudomyelin membranes, magnification 3000 ×. B. Detail of one lamellar body, 8000 ×. C. lung tissue form the patient's biopsy, showing a type II cell with smaller, denser lamellar bodies. D. Detail of one lamellar body with poorly structured content, Magnification bar: 1 μm.

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