Table 2 Patient characteristics II- Airway hyperresponsiveness (AHR) and airway inflammation
From: Airway inflammation and mannitol challenge test in COPD
Subjects | n= 28 |
|---|---|
Airway responsiveness (n= 26) | |
- AHR to mannitol*(n) | 18 |
- RDR mannitol (%/mg) | 0.044 (0.0204-0.0605) |
- Max dose of mannitol (mg) | 395 (315-635) |
- PD15 mannitol** | 331 (196-635) |
Fraction Exhaled Nitric Oxide | |
- FeNO (ppb) | 14 (9-22.5) |
Sputum (n= 23) | |
- Eosinophils (%) | 0.8 (0.4-3.1) |
- Lymphocytes (%) | 1.4 (1.0-2.4) |
- Macrophages (%) | 18.8 (12.8-22.2) |
- Neutrophils (%) | 77.2 (70.8-86.0) |
- Total cell count (x106/g) | 1.6 (0.5-2.8) |
Blood (n= 28) | |
- Eosinophils (%) | 2.7 (1.8-4.3) |
- Neutrophils (%) | 55.9 (49.8-61.8) |