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Table 2 Patient characteristics

From: Withdrawal of inhaled corticosteroids in individuals with COPD - a systematic review and comment on trial methodology

Study Age Sex Baseline severity of COPD Duration of inhaled steroid use prior to entry into trial Mean baseline FEV 1 Mean baseline number of exacerbations in year preceding trial
WISP 14 > 40 Male & female Post-bronchodilator FEV1 < 80% predicted Minimum 6 months, mean 8 years Withdrawn group: 1.40 L Steroid group: 1.31 L (post-bronchodilator) Withdrawn group: 1.86 Steroid group: 1.93
O'Brien et al 17 40-79 Male Details not provided Details not provided 1.61 L Details not provided
COPE 15 40-75 Male & female Pre-bronchodilator FEV1 25-80% predicted 83% of patients had used for at least 6 months Withdrawn group: 1.69 L Steroid group: 1.78 L (post-bronchodilator) All patients: 1.3
COSMIC 16 40-75 Male & female Pre-bronchodilator FEV1 30-70% predicted Details not provided Withdrawn group: 49.0 Steroid group: 48.1 (pre-bronchodilator % predicted) Details not provided, all patients had 2 or more requiring treatment