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Figure 2 | Respiratory Research

Figure 2

From: Respiratory syncytial virus infection is associated with an altered innate immunity and a heightened pro-inflammatory response in the lungs of preterm lambs

Figure 2

RSV infection is associated with airway structural changes in the preterm lung. (A) Representative H&E stain of lung sections from control preterm lamb and RSV-infected preterm lamb. Long arrows represent epithelial thickening, and the short arrow represents a mitotic figure. Bars = 200 μm. (B) Lung sections from each animal were stained with H&E, and epithelial thickening (epithelial cell proliferation/hyperplasia) was scored (see materials and methods section for scoring system). (C) Representative Periodic Acid Schiff (PAS) stain of lung sections from preterm and full-term lambs comparing control to RSV-infected groups. Lung sections were examined under a 20X field. Bars = 200 μm. The data represent the mean ± SE. *p < 0.05 by ANOVA. NS, p > 0.05.

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