Figure 4
From: The emphysematous lung is abnormally sensitive to TRAIL-mediated apoptosis
Sensitivity to TRAIL-mediated apoptosis correlates with lung destruction. [A] Alveolar density index was measured for every lung sample obtained. Bars represent the means. [B] 4-hydroxy-2-nonenal staining was performed for every subject (except one emphysematous subject) and blindly scored for staining intensity. Bars represent the means. [C] Correlation between TRAIL-induced caspase-3 activation in explants from every subjects and the alveolar density index values. Grey triangles represent non-emphysematous subjects and black triangles represent emphysematous subjects. *p < 0.05, **p < 0.01.