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Figure 5 | Respiratory Research

Figure 5

From: Pseudomonas aeruginosa toxin ExoU induces a PAF-dependent impairment of alveolar fibrin turnover secondary to enhanced activation of coagulation and increased expression of plasminogen activator inhibitor-1 in the course of mice pneumosepsis

Figure 5

Immunohistochemical localization of PAI-1. In lung sections from control mice (A) and from mice infected with the bacterial mutant (B) PAI-1 staining was almost resctricted to the bronchiolar epithelium (arrows). Sections from mice infected with the ExoU-producing bacteria exhibited dark brown diaminobenzidine signals in intraalveolar fibrilar material reminiscent of hyaline membrane (arrows in C and E) and in type II pneumocytes (arrows in D). Original magnification: A-B, × 20; C, × 40; D and E, × 100. Photomicrographs are representative of sections from seven animals from each group.

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Respiratory Research

ISSN: 1465-993X

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