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Figure 6 | Respiratory Research

Figure 6

From: Hypoxia-inducible factor-1 α/platelet derived growth factor axis in HIV-associated pulmonary vascular remodeling

Figure 6

Increased expression of PDGF-B chain in HIV-Tg rats compared to wild type controls. A) Real-Time RT-PCR analysis of total mRNA in the lungs of HIV-Tg rats and age matched wild-type SD rats. B) Correlation of PDGF-B chain mRNA with the expression of HIF-1α in HIV-Tg rats. C) Immuno-histochemistry for PDGF-BB on the paraffin embedded lung sections from HIV-Tg and WT rats. Original magnification: 60×. D) Correlation of RV/LV+S ratio with the expression of HIF-1α and PDGF-BB in HIV-Tg rats. Correlation was calculated using the non-parametric Spearman's rank correlation coefficient.

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Respiratory Research

ISSN: 1465-993X

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