From: Analysing the eosinophil cationic protein - a clue to the function of the eosinophil granulocyte
Biological Fluid | ECP concentration (ng/mL) | Eosinophils (×10 6)/mL |
---|---|---|
Plasma | ||
   Normal value | 3.5 | 0.104 (±0.033) [112] |
   Ongoing asthma/allergy | 3.5 | N/A [43] |
   S. mansoni infection | 27 | 0.4 (0.2-0.8) [156] |
   Reactive eosinophilia with a inflammation | 75 | 1.9 (±3.2) [112] |
   HES | 243 | 19.9 (±10.9) [112] |
Serum | ||
   Normal value | 7 | N/A |
   Ongoing allergy/asthma | 15 | N/A [43] |
   S. mansoni infection | ~62 | 0.163 |
   Atopic Dermatitis inflammation | ~50 | 0.315 |
   Bacterial infection | ~19 | N/A [72] |
   HES | 45- 198 | 22-58 percent of total cells [111] |
   Renal tumour | ~30 | N/A [123] |
BALF | ||
   Normal value | ~4 | 0.2 (±0.1) |
   Atopic asthma (challenged) | ~40 | 55.0 (±34.3) [97] |
   Drug-induced ARDS | 13.8 | 4 percent of total cells [78] |
Sputum | ||
   Normal value | 95 | 0.2 percent of total cells |
   Asthma | 735 | 13.4 percent of total cells |
   Eosinophil bronchitis | 604 | 12.4 percent of total cells [157] |
   Experimental Viral Day -5 | 119.1 (8.9-1,146) | 9.3 (0-30.3) percent of total cells |
   Rhinovirus infection Day 2 | 190.6 (17.2-800) b) | 7.5 (0.1-34.4) percent of total cells |
   Day 9 | 157.9(27.8-800) | 5.5 (0.4-23.3) percent of total cells [136] |
Nasal lavage | ||
   Normal value | 3-31 | N/A [158] |
   Allergic rhinitis | 9 ± 2.4 | 19 (±2.1) percent of total cells |
   Allergic rhinitis 6 hr after allergen challenge | 36.6 ± 12 | 56.7 (±5.8) percent of total cells [159] |
Nasal secretions | ||
   Normal value | 56.2 (33.5-94.2) |  |
   RSV infection | 379 (269-532) [75] |  |
   Natural cold | 13038 |  |
   Severe community acquired bacterial sinusitis | 117 704 [77] |  |
Tears | ||
   Normal value | <20 | 1 (±0.2) cells/mm2 in subepithelium [160] |
   Atopic keratoconjunctivitis | 215 (36-1900) [161] | N/A |
   Vernal keratoconjunctivitis | 470 (19-6000) [161] | 112 (±37) cells/mm2 in subepithelium [160] |
Skin, cutaneous | ||
   Normal | N/A |  |
   Atopic dermatitis | >16 000 [64] |  |