Table 1 ECP level in biological fluids and tissues
From: Analysing the eosinophil cationic protein - a clue to the function of the eosinophil granulocyte
| Biological Fluid | ECP concentration (ng/mL) | Eosinophils (×10 6)/mL |
|---|---|---|
| Plasma | ||
| Normal value | 3.5 | 0.104 (±0.033) [112] |
| Ongoing asthma/allergy | 3.5 | N/A [43] |
| S. mansoni infection | 27 | 0.4 (0.2-0.8) [156] |
| Reactive eosinophilia with a inflammation | 75 | 1.9 (±3.2) [112] |
| HES | 243 | 19.9 (±10.9) [112] |
| Serum | ||
| Normal value | 7 | N/A |
| Ongoing allergy/asthma | 15 | N/A [43] |
| S. mansoni infection | ~62 | 0.163 |
| Atopic Dermatitis inflammation | ~50 | 0.315 |
| Bacterial infection | ~19 | N/A [72] |
| HES | 45- 198 | 22-58 percent of total cells [111] |
| Renal tumour | ~30 | N/A [123] |
| BALF | ||
| Normal value | ~4 | 0.2 (±0.1) |
| Atopic asthma (challenged) | ~40 | 55.0 (±34.3) [97] |
| Drug-induced ARDS | 13.8 | 4 percent of total cells [78] |
| Sputum | ||
| Normal value | 95 | 0.2 percent of total cells |
| Asthma | 735 | 13.4 percent of total cells |
| Eosinophil bronchitis | 604 | 12.4 percent of total cells [157] |
| Experimental Viral Day -5 | 119.1 (8.9-1,146) | 9.3 (0-30.3) percent of total cells |
| Rhinovirus infection Day 2 | 190.6 (17.2-800) b) | 7.5 (0.1-34.4) percent of total cells |
| Day 9 | 157.9(27.8-800) | 5.5 (0.4-23.3) percent of total cells [136] |
| Nasal lavage | ||
| Normal value | 3-31 | N/A [158] |
| Allergic rhinitis | 9 ± 2.4 | 19 (±2.1) percent of total cells |
| Allergic rhinitis 6 hr after allergen challenge | 36.6 ± 12 | 56.7 (±5.8) percent of total cells [159] |
| Nasal secretions | ||
| Normal value | 56.2 (33.5-94.2) | |
| RSV infection | 379 (269-532) [75] | |
| Natural cold | 13038 | |
| Severe community acquired bacterial sinusitis | 117 704 [77] | |
| Tears | ||
| Normal value | <20 | 1 (±0.2) cells/mm2 in subepithelium [160] |
| Atopic keratoconjunctivitis | 215 (36-1900) [161] | N/A |
| Vernal keratoconjunctivitis | 470 (19-6000) [161] | 112 (±37) cells/mm2 in subepithelium [160] |
| Skin, cutaneous | ||
| Normal | N/A | |
| Atopic dermatitis | >16 000 [64] | |