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Table 2 Pulmonary function tests of patients with severe asthma

From: Smoking, longer disease duration and absence of rhinosinusitis are related to fixed airway obstruction in Koreans with severe asthma: findings from the COREA study

Characteristics

FAO (n = 119)

RAO (n = 116)

P-value

FEV1, initial, predicted %

54.8 ± 19.9

74.3 ± 22.5

<0.001

FEV1/FVC, initial, predicted %

56.3 ± 11.1

77.6 ± 10.6

<0.001

FEV1/FVC, 3 months after enrollment, predicted %

57.2 ± 10.6

80.0 ± 6.7

<0.001

FEV1/FVC, 12 months after enrollment, predicted %

58.9 ± 9.6

80.9 ± 7.1

<0.001

Baseline PC20, mg/dL*

2.7 ± 4.1

5.6 ± 6.4

0.036

  1. *Baseline methacholine bronchial provocation tests were done in 65 subjects:
  2. 33 patients with FAO (n = 119), 32 patients with RAO (n = 116)
  3. Abbreviations:
  4. FAO, fixed airway obstruction; RAO, reversible airway obstruction; FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity; PC20, provocation concentration that caused a 20% decrease in FEV1
  5. Data are presented as mean ± SD.
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Respiratory Research

ISSN: 1465-993X

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