Skip to main content
Figure 4 | Respiratory Research

Figure 4

From: Lipocalin 2 is protective against E. coli pneumonia

Figure 4

Lcn2 knock-out mice are highly susceptible to lung infection with E. coli H9049. (A) Survival curves of wild-type (wt) (n = 12) and lipocalin 2 knock-out (ko) (n = 16) mice infected with 4 Ă— 107 CFU E. coli H9049/mouse demonstrating a significant higher mortality (p < 0.05) of the knock-out mice. Box plots showing bacterial numbers (CFUs) for the surviving mice (ko (n = 9) and wt (n = 11)) in the lungs (B) and spleens (C). A significantly higher number of bacteria were found in both the lungs (p < 0.05) and spleens (p < 0.05) of Lcn2 knock-out mice than in wild-type mice.

Back to article page