From: Isolation and characterization of microparticles in sputum from cystic fibrosis patients
Stable CF | Acute CF | p | PCD | |
---|---|---|---|---|
N | 11 | 10 | 7 | |
Age (years) | 23.4 ± 4.3 | 24.5 ± 3.7 | 22.7 ± 3.5 | |
Sex ratio (male:female) | 7:4 | 2:8 | 3:4 | |
F508del homozygous | 5 | 2 | / | |
F508del heterozygous | 4 | 7 | / | |
Other mutations | 1 | 1 | / | |
FEV1 (%) | 57.8 ± 7.0 | 49.6 ± 6.4 | 0.53 | 75.2 ± 8.4 |
ΔFEV1 | 9.08 ± 2.5 | 0.07 ± 0.04 | 0.001 | / |
CRP (mg/dl) | 0.53 ± 0.16 | 8.36 ± 2.87 | 0.01 | / |
Clinical score | 7.3 ± 0.37 | 2.45 ± 0.31 | 0.001 | / |
Source of infection: | ||||
Pseudomonas aeruginosa | 11 | 6 | 3 | |
Staphylococcus aureus | 3 | 3 | 0 | |
Burkholderia cepacia complex | 0 | 2 | 0 | |
Alcaligenes xilosoxidans | 0 | 1 | 0 |