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Figure 3 | Respiratory Research

Figure 3

From: Histamine H4 receptor antagonism diminishes existing airway inflammation and dysfunction via modulation of Th2 cytokines

Figure 3

An H 4 R antagonist inhibits sub-chronic allergic airway inflammation in Balb/C mice. (A) The total number of white blood cells (WBCs) and differential cell count for eosinophils, monocytes neutrophils and lymphocytes were calculated from BAL fluid collected after the final OVA challenge. JNJ 7777120 was dosed at 20 mg/kg. n = 8-10 (B) Lung histology, hematoxylin and eosin stain (x200 magnification). Significance of each treatment group compared to control vehicle-treated animals is as follows: * P < 0.05, ** P < 0.01.

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