Figure 6

Assessment of allergen-induced airway hyperresponsiveness by negative pressure-driven forced expiratory parameters. Forced expiration parameters at baseline (BL) and following aerosolized saline (Sal) or increasing methacholine concentrations in vehicle (Veh)- or dexamethasone (Dex)-treated, sham (Sal)- and ovalbumin (OVA)-challenged ovalbumin-sensitized mice. Values were obtained at peak response to each concentration of aerosolized methacholine and are expressed as mean ± standard deviation from groups of 4-6 mice where each animal was studied once. (*p < 0.05 Veh/OVA vs Veh/Sal, ^#p < 0.05 Veh/OVA vs Dex/OVA; ANOVA).