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Figure 2 | Respiratory Research

Figure 2

From: Nebulization of the acidified sodium nitrite formulation attenuates acute hypoxic pulmonary vasoconstriction

Figure 2

Dose titration for nebulized nitrite in the isolated perfused lung model. Nitrite was nebulized in increasing concentrations during hypoxic maneuvers. (A) HPV was calculated as the difference between the maximum Ppa during hypoxia and the Ppa during normoxia. (B) Lung weight gain during nebulization. Lungs were freely suspended from a force transducer for monitoring organ weight in a humidified chamber at 39°C. Weight changes were monitored continuously. Values represent differences in lung weight before and after each nebulization procedure. * p < 0.05 vs. PB.

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Respiratory Research

ISSN: 1465-993X

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