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Table 1 Symptoms of wheeze in the past 12 months - summary of ecological analyses*.

From: Which population level environmental factors are associated with asthma, rhinoconjunctivitis and eczema? Review of the ecological analyses of ISAAC Phase One

Ecological Issue

Specific Factor

13-14 Year Age Group

6-7 Year Age Group

  

Written Questionnaire

Video Questionnaire

Written Questionnaire

  

Direction of effect

P Value

Direction of effect

P Value

Direction of effect

P value

Economic development

GNP

+

0.007

+

0.08

+

0.84

Diet

Calories from cereals and rice %

-

0.0005

-

0.07

-

0.021

 

Protein from cereals and nuts %

-

0.002

-

0.015

-

0.062

 

Starch g/day

-

0.008

-

0.01

-

0.036

 

Vegetables g/d

-

0.041

-

0.205

-

0.262

 

Vegetable Vitamin A μ/d

-

0.04

-

0.159

-

0.235

 

Trans fatty acids

+

< 0.0001

+

< 0.05

  

Immunisation

Local immunisation rates for DTP#

-

0.047

  

-

> 0.05

 

Local immunisation rates for measles

-

> 0.05

  

-

> 0.05

TB exposure

TB notification rates

-

0.344

-

0.018

  
 

Estimated TB incidence rates

-

0.262

-

0.263

-

< 0.0001

Outdoor climate

Altitude

-

> 0.05

+

> 0.05

-

> 0.05

 

Annual variation in mean temperature

-

> 0.05

-

> 0.05

-

> 0.05

 

Lowest monthly mean temperature

+

> 0.05

0

> 0.05

+

> 0.05

 

Annual variation in mean relative humidity

-

> 0.05

+

> 0.05

-

> 0.05

 

Lowest monthly mean relative humidity

0

> 0.05

-

> 0.05

0

< 0.05

 

Mean relative humidity of ≥ 1 month < 50%humidity

+

> 0.05

+

> 0.05

+

> 0.05

Indoor climate

Mean annual relative humidity

0

> 0.05

-

> 0.05

-

> 0.05

 

Lowest monthly mean relative humidity

+

> 0.05

0

> 0.05

0

> 0.05

Tobacco smoking

Tobacco consumption, ≥ 15 yrs

0

0.92

+

0.53

+

0.46

 

Tobacco smoking, women

+

0.06

+

0.72

+

0.32

 

Tobacco smoking, men

-

0.001

-

0.004

-

0.06

Pollen

Total grass pollen count

-

0.67

    
 

Days with high pollen counts

-

0.39

    

Antibiotic usage

Antibiotic sales per capita

-

0.21

+

0.01

  

Air pollution

PM10

-

0.03

  

-

0.06

Paracetamol

Per capita paracetamol sales

+

< 0.0005

  

+

0.001

  1. *standardized for GNP. Where p values are recorded as > 0.05 the non significant p values were not provided in the source publication. #DTP = Diphtheria and tetanus toxoids and pertussis.
  2. Blank space = data not collected. + = positive association. - = inverse association. 0 = no association.