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Table 8 Univariate associations between serum biomarkers and neutrophil total counts and % in blood and sputum.

From: Sputum neutrophils as a biomarker in COPD: findings from the ECLIPSE study

 

No of subjects

Median (IQR)

Blood neutrophils

Sputum neutrophils

   

Total Count

%

Total count/ml

%

C-RP

mg/L

134

6.3 (11.0)

r2 = 0.05 ; p = 0.011

NS

NS

r2 = 0.02; p = 0.070

IL-6

pg/ml

331

1.9 (4.3)

r2 = 0.03; p = 0.001

r2 = 0.03; p = 0.001

NS

NS

IL-8

pg/ml

332

7.7 (7.6)

NS

NS

NS

r2 = 0.02; p = 0.019

SP-D

ng/ml

279

126.7 (90.6)

NS

NS

r2 = 0.02; p = 0.016

NS

  1. IQR = interquartile range. NS = statistically non-significant