Table 5 Linear and multivariate analysis of relationship between SGRQ score and sputum neutrophil percentage at year 1.
From: Sputum neutrophils as a biomarker in COPD: findings from the ECLIPSE study
| Â | Linear Regression | Â | Multiple Regression | ||||
|---|---|---|---|---|---|---|---|
Independent Variables in Model | Estimate(SE) | p-value | R-square | Â | Estimate(SE) | p-value | R-square |
Age | -0.174 (0.185) | 0.348 | 0.003 | Â | -0.282 (0.175) | 0.108 | 0.208 |
BMI | 0.244 (0.213) | 0.252 | 0.004 | Â | 0.391 (0.207) | 0.060 | Â |
Concomitant ICS use | -9.516 (2.814) | <0.001 | 0.038 | Â | -3.751 (2.803) | 0.182 | Â |
Current smoking status | -3.060 (2.454) | 0.214 | 0.005 | Â | -1.049 (2.403) | 0.663 | Â |
Number of exacerbations during year 1 | 3.936 (0.666) | <0.001 | 0.107 | Â | 3.230 (0.683) | <0.001 | Â |
Pack years | 0.146 (0.042) | <0.001 | 0.039 | Â | 0.157 (0.040) | <0.001 | Â |
FEV1 % predicted | -0.320 (0.076) | <0.001 | 0.057 | Â | -0.190 (0.081) | 0.020 | Â |
Gender | 0.633 (2.565) | 0.805 | 0.000 | Â | 3.038 (2.490) | 0.223 | Â |
Sputum neutrophil % | 0.205 (0.080) | 0.011 | 0.022 | Â | 0.138 (0.078) | 0.079 | Â |