Table 4 Linear and multivariate analysis of relationship between SGRQ score and sputum neutrophil percentage at the baseline visit.
From: Sputum neutrophils as a biomarker in COPD: findings from the ECLIPSE study
| Â | Linear Regression | Â | Multiple Regression | ||||
|---|---|---|---|---|---|---|---|
Independent Variables in Model | Estimate(SE) | p-value | R-square | Â | Estimate(SE) | p-value | R-square |
Age | -0.453 (0.148) | 0.002 | 0.026 | Â | -0.471 (0.147) | 0.001 | 0.179 |
BMI | 0.387 (0.176) | 0.028 | 0.014 | Â | 0.428 (0.174) | 0.014 | Â |
Concomitant ICS use | -6.813 (2.333) | 0.004 | 0.024 | Â | -2.666 (2.293) | 0.246 | Â |
Current smoking status | -1.941 (2.077) | 0.351 | 0.003 | Â | -1.062 (2.089) | 0.611 | Â |
Pack years | 0.051 (0.036) | 0.163 | 0.006 | Â | 0.086 (0.035) | 0.014 | Â |
Number of prior exacerbations | 2.973 (0.649) | <0.001 | 0.057 | Â | 1.923 (0.651) | 0.003 | Â |
FEV1 % predicted | -0.328 (0.065) | <0.001 | 0.069 | Â | -0.307 (0.068) | <0.001 | Â |
Gender | 1.571 (2.115) | 0.458 | 0.002 | Â | 4.083 (2.121) | 0.055 | Â |
Sputum neutrophil % | 0.113 (0.063) | 0.077 | 0.009 | Â | 0.130 (0.061) | 0.035 | Â |