Panel A: Individual levels of LXA
in supernatants of alveolar macrophages before and after lipopolysaccharide (LPS) from normal subjects (n = 14), non-severe asthmatics (n = 12) and severe asthmatics (n = 11). In the asthmatic groups, closed symbols indicate those on regular treatment with inhaled and/or oral corticosteroids. Panel B: Mean levels of LXA4 induced by LPS (level after LPS minus basal level) in the 3 groups. Data shown as mean ± SEM.