↑[100, 144, 145] | ↑[100, 146] | Oxidative Stress/Cell damage | ↑* [15, 147, 148] | ↑[15, 86, 149–151] |
↑[18, 152] | ↑[100, 134, 146, 153, 154], f[155] | TNFα | ~[156, 157] | ↑[106, 158–161], ↓[107] |
↑[18, 152] | ↑[100, 162, 163], f [162] | IL-1β | ↑* [148], ~[156] | ↑[135, 150, 161], ↓[159] |
↑[18, 152] | ↑[95, 163], ~[153] | IL-6 | ↑[157, 164], ~[165] | ↑[158, 160], f[161] |
↑[18, 152] | ↑[95, 100, 153, 154, 163] | IL-8/KC | ↑[17, 156, 166], ↑* [148, 167–170], ~[165] | ↑[125, 135, 160] |
↑[18, 152] | ↑[95, 100, 134, 153, 154] | MCP-1 | ↑* [170] | ↑[125, 150, 160], ~[111] |
↑,~[171] | ↑ [95], f[171] | GM-CSF | ↑* [148, 167–169], ~[156, 165], f* [128] | ↑[172], f[172], ↓[106], ~[104] |
~[173] | ~[89] | Eotaxin | ↑* [174], ~[175] | ↑[112], ~[111] |
↑[176] | ↑[126] | TSLP | ↑* [127], f* [127] | ▪ |
↑ [177–179] | ↑[134, 154, 180], ↓[181] | Dendritic cell number | ▪ | ↑[125] |
▪ | ↑[72], ~[181] | DC transport of antigen | ▪ | ↑[125] |
↑[177, 182] | ↑[72, 134, 180], ↓[181] | Costimulatory molecule expression | ↑* [127, 128] | ↑[84, 125] |
~or ↑[183, 184] | ▪ | Eosinophil number or degranulation | ↑* [185], ~[175, 186], | ↑[109], ~[106, 107, 110] |
↑[16, 18, 101, 187] | ↑[134, 153, 154, 180] | Neutrophil number | ↑[15, 17, 157, 175, 186, 188] | ↑[86, 104, 106, 107, 110, 112, 125, 158, 159] |
↑[16, 101] | ↑[134, 153, 154, 180] | T or B-cell number | ↑[15, 17, 157, 175, 188], ~[186] | ↑[159], ~[104, 110] |
↑[28, 44], ~[25, 27] | ↑[95], ~[93] | IgE | ↑[15, 123, 189] | ~[86, 104, 106, 107, 109, 110] |
↑[190] | ~[153] | IgG | ~[123, 189] | ~[86, 104, 106, 107, 109, 110] |
Human
|
Mouse
|
EFFECTS IN ALLERGIC DISEASE
|
Human
|
Mouse
|
â–ª |
f [73], ↑[63, 73], ~[71] | GM-CSF | ↑* [168, 169], ~[165] | ↑[85], ↓[107] |
↑[173] | ↑[70, 89, 93] | Eotaxin | ▪ | ↑[85, 88, 111, 112] |
↑[46] | ↑[63, 72, 90], ↓[70, 73] | Neutrophil number | ↑[166], ~[17] | ↑[104–106, 108, 110, 112] |
↓[191] | ↑[64, 72, 73, 93, 94, 192], ↓[70, 92] | T or B-lymphocyte number | ↑[193], ~[17] | ↑[84, 85, 104, 105, 108–111] |
↓[173, 194] | ↑[63–65, 68, 69, 71–73, 89, 94], ↓[70, 96], ~[92] | Eosinophil number | ~[17] | ↑[83, 85, 87, 88, 104–106, 109–111] |
▪ | ↓[96] | T- or B-cell proliferation | ↑[193] | ↑[76, 77, 79, 84, 131] |
↓[191] | ↑[71–73, 93, 94], ↓[70] | Dendritic cell number | ▪ | ▪ |
▪ | ↑[72] | Costimulatory molecule expression | ↑[195] | ↑[84, 131] |
↑[194] | ↑[90] | Mast cell number | ↑[166] | ↑[108] |
↑[29] | ↑[64, 70], ↓[96] | IL-4 | ↑[55, 123, 193] | ↑[76–78, 84, 131], ↓ [107] |
↑[29], ↓[173] | ↑[63, 65, 68, 70, 71, 73, 89], ↓[96] | IL-5 | ↑[85, 123] | ↑[85, 88, 104–107, 109–112, 131] |
↑[29] | ↑[65, 70, 72] | IL-13 | ↑[123] | ↑[112, 131] |
↑[29, 44] | ↑[63–65, 71, 73, 93], ~[67–70, 90, 92, 94] | IgE | ↑[15, 55, 56, 123] | ↑[74–84, 86, 87, 104, 105, 107, 108], ~[106, 110] |
▪ | ↑[63–65, 71, 73], ↓[96] | IgG | ↑[56, 123], ~[55] | ↑[81, 82, 84–86, 88, 104, 105, 107–109, 111, 112], ~[106, 110] |
↑[29] | ▪ | Histamine | ↑[15, 196] | ▪ |
↑[30, 32] | ↑[66, 68, 68, 69, 89–91, 93], ~[67, 71], ↓[70, 92] | Airway hyperresponsiveness | ↑[15, 17, 59] | ↑ [105–108] |
↑[194] | ↑[89, 90], ~[95] | Airway wall remodeling | ▪ | ↑[110] |
↑[194] | ↑[72, 73, 89, 90], ↓[70] | Goblet cell hyperplasia | ▪ | ↑[83, 85, 87, 106–108, 110, 111] |
