Figure 9

IRAK-1 and TRAF6 mRNA and protein expression following exposure to IL-1β and miR-146a mimic. HASM cells were transfection with either miR-146a mimics or control and then exposed to either vehicle control or 1 ng/ml IL-1β and the expression of IRAK-1 and TRAF6 mRNA (A) and protein (B) were detected at 24 h. The results in panel A are mean ± SEM of three independent experiments where * p < 0.05 versus time-matched controls whilst panel B is representative of three independent experiments.