hybridization targeting NTHI in
infected human lung tissue (Aminoethylcarbazole, red signals). Signals are also indicated by arrows. Positive staining of AM (A, 400×), AEC (B, 400×) and bronchial epithelial cells (C, 400×), control (D, 400×). NTHI-1 infection was primarily detected in AM (figure a) and to a lesser degree also in AEC (figure 2b). Similar results were seen with NTHI-2 (demonstrated for AM [E, 600×], control [F, 600×]). AM = alveolar macrophages, AEC = alveolar epithelial cells.