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Table 2 Adenosine 5'-monophosphate provocation test data at 09:00 hours, immediately before administration of study treatments

From: Protective effect of budesonide/formoterol compared with formoterol, salbutamol and placebo on repeated provocations with inhaled AMP in patients with asthma: a randomised, double-blind, cross-over study

Treatment

Baseline FEV1, before provocation (L)

AMP dose (mg/ml)

Fall in FEV1 after AMP provocation (%)

Increase in Borg dyspnoea score after provocation

Budesonide/formoterol

3.13 (0.80)

109 (184)

28.0 (14.0)

2.50 (1.40)

Formoterol

3.11 (0.86)

122 (193)

28.7 (12.2)

2.00 (1.35)

Salbutamol

3.03 (0.91)

110 (191)

31.6 (14.5)

2.91 (1.58)

Placebo

3.06 (0.89)

106 (186)

29.4 (10.6)

2.79 (1.57)

  1. All data are presented as mean (SD); FEV1: forced expiratory volume in 1 second; AMP: adenosine 5'-monophoshate; AMP dose as cumulative nebulized concentration.