| Mac | Epi | Eos | Neut | Lymph |
---|
C57-PBS
| 5.2 ± 1.0 | 5.5 ± 1.9 | 0.03 ± 0.02 | 0.02 ± 0.01 | 0.09 ± 0.03 |
PAR2-/- PBS
| 5.1 ± 1.4 | 7.3 ± 2.4 | 0.04 ± 0.02 | 0.05 ± 0.02 | 0.1 ± 0.04 |
C57-frass
| 35.1 ± 11 | 16.9 ± 7.1 | 11.7 ± 3.4 | 17 ± 7.9 | 23.4 ± 7.9 |
PAR2-/- frass
| 32.8 ± 9.9 | 8.6 ± 4.2 | 19.2 ± 5.6 | 14.1 ± 6.7 | 21.0 ± 7.0 |
- Wild type (C57Bl/6) or PAR-2-deficient mice were given intraperitoneal injections of PBS or GC frass with alum on day 0 and 7. Intratracheal inhalations of PBS or GC frass were performed on days 14 and 19. On day 22, BAL fluid was harvested and differential cell counts performed. These data represent 9 mice per group and are expressed as mean ± SEM of cell number × 104. Cell counts were statistically significant between GC frass and PBS exposed mice (*p < 0.05, as determined by ANOVA). There was no statistically significant difference between mice C57Bl/6 and PAR-2-deficient mice exposed to GC frass