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Table 1 Clinical characteristics of COPD patients and controls with airway biopsy available.

From: Multidrug resistance-associated protein-1 (MRP1) genetic variants, MRP1 protein levels and severity of COPD

 

COPD patients (n = 114)

Controls (n = 37)

Males, n (%)

99 (86.8)

16 (43.2)

Age (years)

61.6 ± 7.7

52.3 ± 5.5

Height (cm)

175.5 ± 7.8

172.8 ± 10

Packyears¶

41.8 (31.2 - 54.7)

25.4 (20.2-35.0)

Current smoker, n (%)

72 (63.2)

30 (81.1)

FEV1/FVC (%)

49.5 ± 8.8

77.2 ± 6.1

FEV1 (L)

1.8 ± 0.4

3.2 ± 0.8

FEV1 % pred.*

56 ± 10

100 ± 14

MRP1 level #, n

80

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  1. Data are presented as mean ± standard deviation or ¶ median (25th - 75th percentile); FEV1 = forced expiratory volume in one second; FEV1/FVC = FEV1/forced vital capacity; * % pred. = percentage of predicted value; # refers to the number of individuals having bronchial biopsies with available MRP1 levels of intensity; MRP1 = multidrug resistance-associated protein-1