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Table 1 Anthropometric characteristics, spirometric values and drug regimen of the subjects.

From: Deregulation of apoptosis mediators' p53 and bcl2 in lung tissue of COPD patients

 

COPD smokers

Non-COPD smokers

*P value

Number

23

20

 

Sex (M/F)

23/0

20/0

 

Age (years)

64 ± 7*

57 ± 10*

0.03

Smoking (P-Y)

60 ± 21*

50 ± 27*

NS

FEV1 (% pred.)

64 ± 16*

95 ± 13*

0.0001

FVC (% pred)

80 ± 18*

91 ± 13*

0.02

FEV1/FVC (%)

63 ± 6.5*

82 ± 5*

0.0001

IPRATOPIUM

or

TIOTROPIUM

20 mcg, ×3/day

Once daily

NA

 

ICS

100 mcg ×2/day

NA

 
  1. M/F: Male/Female
  2. P-Y: pack years of smoking (mean ± SD)
  3. FEV1: forced expiratory volume in 1 second (mean ± SD)
  4. FVC: forced vital capacity (mean ± SD)
  5. ICS: inhaled corticosteroids (BUDESONIDE or BECLOMETHAZONE or FLUTICAZONE)
  6. NS: non-significant
  7. NA: not applicable