From: Deregulation of apoptosis mediators' p53 and bcl2 in lung tissue of COPD patients
 | COPD smokers | Non-COPD smokers | *P value |
---|---|---|---|
Number | 23 | 20 | Â |
Sex (M/F) | 23/0 | 20/0 | Â |
Age (years) | 64 ± 7* | 57 ± 10* | 0.03 |
Smoking (P-Y) | 60 ± 21* | 50 ± 27* | NS |
FEV1 (% pred.) | 64 ± 16* | 95 ± 13* | 0.0001 |
FVC (% pred) | 80 ± 18* | 91 ± 13* | 0.02 |
FEV1/FVC (%) | 63 ± 6.5* | 82 ± 5* | 0.0001 |
IPRATOPIUM or TIOTROPIUM | 20 mcg, ×3/day Once daily | NA |  |
ICS | 100 mcg ×2/day | NA |  |