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Table 1 Anthropometric characteristics, spirometric values and drug regimen of the subjects.

From: Deregulation of apoptosis mediators' p53 and bcl2 in lung tissue of COPD patients

  COPD smokers Non-COPD smokers *P value
Number 23 20  
Sex (M/F) 23/0 20/0  
Age (years) 64 ± 7* 57 ± 10* 0.03
Smoking (P-Y) 60 ± 21* 50 ± 27* NS
FEV1 (% pred.) 64 ± 16* 95 ± 13* 0.0001
FVC (% pred) 80 ± 18* 91 ± 13* 0.02
FEV1/FVC (%) 63 ± 6.5* 82 ± 5* 0.0001
IPRATOPIUM
or
TIOTROPIUM
20 mcg, ×3/day
Once daily
NA  
ICS 100 mcg ×2/day NA  
  1. M/F: Male/Female
  2. P-Y: pack years of smoking (mean ± SD)
  3. FEV1: forced expiratory volume in 1 second (mean ± SD)
  4. FVC: forced vital capacity (mean ± SD)
  5. ICS: inhaled corticosteroids (BUDESONIDE or BECLOMETHAZONE or FLUTICAZONE)
  6. NS: non-significant
  7. NA: not applicable