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Table 1 Demographic and pulmonary function characteristics of 16 COPD patients and 8 control subjects from whose lung biopsies were used for immunohistochemical detection of CD1a+ Langerhans cells and CD83+ mature dendritic cells.

From: Cigarette smoke promotes dendritic cell accumulation in COPD; a Lung Tissue Research Consortium study

 

Controls

COPD

P value

Gender M:F

2:6

9:7

 

Age - median (range)

63.5 (56-78)

65.5 (49-78)

0.779

Smoking history (pack years)

   

Median (range)

50.0 (2-110)

51.5 (5-180)

0.625

FEV1 (% predicted)

   

Median (range)

88.0 (78-107)

43.5 (27-75)

<0.001

FEV1/FVC - Median

101.5

59.7

<0.001

DLCO (% predicted)

   

Median (range)

62.0 (34-122)

54.0 (27-99)

0.416