Table 4 Multivariable Cox Regression Models for Survival in PiZZ Individuals*

Gender

0.90

Male

635

1.00

0.80-1.30

0.90

Female

674

1.0

Age at inclusion, years

<0.001

>50

580

5.50

4.0-7.50

<0.001

≤50

729

1.0

Pre-bronchodilator FEV₁ % of predicted

<0.001

183

4.30

2.90-6.40

<0.001

< 30

230

2.00

<0.001

30-49

263

1.60

1.40-3.00

0.020

50-79

633

1.0

≥ 80

1.10-2.40

Respiratory symptoms at inclusion^&

0.001

Yes

820

2.20

1.40-3.50

0.001

No

489

1.0