Skip to main content

Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Table 4 Multivariable Cox Regression Models for Survival in PiZZ Individuals*

From: Survival in severe alpha-1-antitrypsin deficiency (PiZZ)

  No. Risk Ratio 95%CI P value
Gender     0.90
Male 635 1.00 0.80-1.30 0.90
Female 674 1.0   
Age at inclusion, years     <0.001
>50 580 5.50 4.0-7.50 <0.001
≤50 729 1.0   
Pre-bronchodilator FEV1 % of predicted     <0.001
  183 4.30 2.90-6.40 <0.001
< 30 230 2.00   <0.001
30-49 263 1.60 1.40-3.00 0.020
50-79 633 1.0   
≥ 80    1.10-2.40  
Respiratory symptoms at inclusion&     0.001
Yes 820 2.20 1.40-3.50 0.001
No 489 1.0   
  1. ** 1309 individuals with complete data on included predictors.
  2. &irrespective of mode of identification.