From: Partial pulmonary embolization disrupts alveolarization in fetal sheep
 | Study 1 | Study 2 | |||
---|---|---|---|---|---|
 | Age-matched control, 130d GA | 1d PPE + 15d, 130d GA | 5d PPE + 16d, 130d GA | Age-matched control, 116d GA | 5d PPE, 116d GA |
Body wt (kg) | 3.4 ± 0.1 | 3.2 ± 0.3 | 3.5 ± 0.2 | 2.5 ± 0.4 | 2.3 ± 0.2 |
Wet lung wt/Body wt (g/kg) | 33.2 ± 1.7 | 33.8 ± 2.1 | 31.2 ± 2.8 | 39.4 ± 5.4 | 34.3 ± 3.6 |
Heart wt/Body wt (g/kg) | 7.4 ± 0.2 | 6.6 ± 0.1* | 6.9 ± 0.3 | 6.3 ± 0.3 | 7.6 ± 0.2* |
Liver wt/Body wt (g/kg) | 27.3 ± 1.4 | 24.5 ± 2.2 | 30.2 ± 2.3 | 27.9 ± 3.7 | 38.9 ± 2.3 |
Left Kidney wt/Body wt (g/kg) | 3.1 ± 0.1 | 2.9 ± 0.1 | 3.4 ± 0.1 | 3.7 ± 0.2 | 4.0 ± 0.2 |
Right Kidney wt/Body wt (g/kg) | 3.1 ± 0.2 | 2.8 ± 0.2 | 3.3 ± 0.1 | 3.8 ± 0.2 | 3.9 ± 0.2 |
Total Lung Volume/Body wt (cm3/kg) | 27.3 ± 1.7 | 29.2 ± 2.9 | 26.8 ± 3.0 | N.D. | N.D. |
Left Lung Volume/Body wt (cm3/kg) | 10.5 ± 0.7 | 10.4 ± 0.7 | 11.0 ± 1.1 | N.D. | N.D. |
Right Lung Volume/Body wt (cm3/kg) | 16.7 ± 1.0 | 18.8 ± 2.3 | 15.7 ± 2.0 | N.D. | N.D. |