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Table 2 Fetal body weights (kg), organ weights (g/kg) and lung volumes (cm3/kg) for fetuses in PPE treatment groups compared to corresponding age-matched control group (* p < 0.05).

From: Partial pulmonary embolization disrupts alveolarization in fetal sheep

  Study 1 Study 2
  Age-matched control,
130d GA
1d PPE + 15d,
130d GA
5d PPE + 16d,
130d GA
Age-matched
control,
116d GA
5d PPE, 116d GA
Body wt
(kg)
3.4 ± 0.1 3.2 ± 0.3 3.5 ± 0.2 2.5 ± 0.4 2.3 ± 0.2
Wet lung wt/Body wt
(g/kg)
33.2 ± 1.7 33.8 ± 2.1 31.2 ± 2.8 39.4 ± 5.4 34.3 ± 3.6
Heart wt/Body wt
(g/kg)
7.4 ± 0.2 6.6 ± 0.1* 6.9 ± 0.3 6.3 ± 0.3 7.6 ± 0.2*
Liver wt/Body wt
(g/kg)
27.3 ± 1.4 24.5 ± 2.2 30.2 ± 2.3 27.9 ± 3.7 38.9 ± 2.3
Left Kidney wt/Body wt
(g/kg)
3.1 ± 0.1 2.9 ± 0.1 3.4 ± 0.1 3.7 ± 0.2 4.0 ± 0.2
Right Kidney wt/Body wt (g/kg) 3.1 ± 0.2 2.8 ± 0.2 3.3 ± 0.1 3.8 ± 0.2 3.9 ± 0.2
Total Lung Volume/Body wt (cm3/kg) 27.3 ± 1.7 29.2 ± 2.9 26.8 ± 3.0 N.D. N.D.
Left Lung Volume/Body wt (cm3/kg) 10.5 ± 0.7 10.4 ± 0.7 11.0 ± 1.1 N.D. N.D.
Right Lung Volume/Body wt (cm3/kg) 16.7 ± 1.0 18.8 ± 2.3 15.7 ± 2.0 N.D. N.D.
  1. (ND = not determined)