Skip to main content

Table 6 Within-subject and between-subject coefficients of variation, analytical variation, reference change value in COPD induced sputum samples:

From: Multi analyte profiling and variability of inflammatory markers in blood and induced sputum in patients with stable COPD

Sputum Protein Within-subject CV (%) (90% CI) Between-subject CV (%) (90% CI) Analytical variation (%) Reference change value (%)
Eotaxin2 70 (53 - 95) 88 (50 - 104) 12.1 196.77
HGF 58 (44 - 76) 66 (46 - 79) 14.3 165.47
IP-10 62 (45 - 82) 54 (32 - 73) 12.2 175.03
KGF 49 (33 - 70) 90 (58 - 126) 8.3 137.66
MMP-13 54 (36 - 72) 69 (43 - 89) 11.0 152.65
TNF-RI 46 (36 - 54) 56 (40 - 65) 8.8 129.73
GROα 78 (56 - 100) 89 (52 - 106) 8.2 217.25
TIMP2 81 (57- 101) 57 (38 - 77) 8.4 225.57
TNF-RII 69 (49 - 89) 104 (65 - 126) 8.6 192.61
α2 macroglobulin 57 (33 - 75) 70 (47 - 84) 6.43 158.89
ENA-78 61 (49 - 74) 88 (60 - 104) 4.32 169.39
IL-13 30 (23 - 37) 101 (32 - 116) 3.25 83.59
IL-15 62 (48 - 76) 121 (64- 149) 3.96 172.09
IL-18 55 (43 - 66) 63 (32 - 73) 3.46 152.65
IL-1β 61 (44 - 77) 160 (113 - 210) 4.58 169.45
IL-1RA 58 (46 - 69) 55 (37 - 68) 5.86 161.48
IL-6 50 (36 - 68) 99 (59 - 118) 3.73 138.88
IL-8 60 (47 - 82) 88 (70 - 106) 3.83 166.54
MCP-1 86 (70 - 99) 146 (84 - 182) 3.95 238.47
MMP-2 57 (39 - 81) 70 (38 - 82) 3.33 158.16
TIMP-1 54 (33- 73) 38 (27 - 46) 5.89 150.47
VEGF 42 (32 - 55) 24 (15 - 31) 4.98 117.15
Median coefficient of variation for all proteins 58 79 5.88 163.47
\