Skip to main content

Table 3 Within-subject and between-subject coefficients of variation, analytical variation and reference change value in COPD serum samples:

From: Multi analyte profiling and variability of inflammatory markers in blood and induced sputum in patients with stable COPD

Serum Protein Within-subject CV (%) (90% CI) Between-subject CV (%) (90% CI) Analytical variation (%) Reference change value (%)
Eotaxin2 64 (55 - 77) 65 (50 - 77) 12.1 180.42
IP-10 49 (44 - 57) 62 (50 - 67) 12.2 139.87
TNF-R1 26 (20 - 33) 20 (13 - 29) 8.8 76.03
TNF-RII 50 (42 - 59) 59 (40 - 68) 8.6 140.53
TIMP-2 21 (17 - 26) 20 (13 - 24) 8.4 62.65
HGF 71 (59 - 84) 56 (37 - 65) 14.3 200.62
KGF 55 (46 - 62) 46 (35 - 57) 8.3 154.08
MMP-13 88 (74 - 103) 151 (57 - 172) 11.0 245.66
GRO╬▒ 32 (26 - 37) 48 (28 - 56) 8.2 91.50
CRP 53 (40 - 69) 94 (67 - 122) 6.05 147.76
ENA-78 16 (13 - 19) 101 (31 - 120) 4.32 45.91
IL-13 19 (18 - 23) 26 (19 - 30) 3.25 53.39
IL-18 21 (17 - 23) 46 (31 - 54) 3.46 58.95
IL-6 34 (24 - 49) 95 (64 - 111) 3.73 94.74
IL-8 30 (20 - 38) 66 (36 - 79) 3.83 83.77
MCP-1 17 (14 - 20) 56 (35 - 70) 3.95 48.34
Myeloperoxidase 36 (31 - 41) 83 (47 - 103) 5.39 100.83
TIMP-1 16 (14 - 18) 18 (13 - 21) 5.89 47.23
VEGF 19 (14 - 27) 63 (28 - 79) 4.98 54.41
Median coefficient of variation for all proteins 32 59 6.05 91.05
\