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Figure 4 | Respiratory Research

Figure 4

From: Intracerebroventricular injection of leukotriene B4 attenuates antigen-induced asthmatic response via BLT1 receptor stimulating HPA-axis in sensitized rats

Figure 4

LTB 4 via i.c.v injection increases CORT and ACTH levels in rat plasma. CORT (A) and ACTH (B) levels in plasma were measured using commercial ELISA kits at 30 min before and after LTB4 i.c.v, and 30 min after antigen challenge. Data are expressed as the mean ± S.D (n = 6 in each group). ##P < 0.01 vs the basal level (pretreatment); **P < 0.01 vs after antigen challenge;$$P < 0.01 vs before antigen challenge; ††P < 0.01 vs the LTB4-OVA group.

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