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Table 1 Characteristics of the patients and comparison between the two groups (unstable vs stable) at PEEP 10.

From: Positive End-Expiratory Pressure may alter breathing cardiovascular variability and baroreflex gain in mechanically ventilated patients

Parameters All patients (n = 23) Unstable group (n = 11) Stable group (n = 12) p (unstable vs stable group)
Age (years) 55 (49-61) 53 (49-60) 56 (49-61) 0.90
SAPS II 61 (49-75) 58 (46-61) 71 (53-79) 0.13
Duration of mechanical ventilation (days) 12 (7-15) 12.0 (6.5-21.8) 12.5 (9.5-15.0) 0.74
PaO2/FiO2 210 (150-293) 242 (154-375) 175 (150-266) 0.48
FiO2 (%) 50 (40-60) 45 (36-59) 50 (40-70) 0.54
PaCO2 (mmHg) 39 (37-45) 40 (37-44) 38 (36-46) 0.76
SOFA score 9.0 (6.3-11.8) 7.0 (5.3-10.0) 10.5 (7.5-14.5) 0.04
Vasoactive drugs dosage (μg.kg-1.min-1) 0.25 (0.00-0.35) 0.13 (0.00-0.25) 0.32 (0.22-0.78) 0.03
  1. All results were reported as median (25-75 percentile) values. PaO2/FiO2, FiO2, PaCO2, SOFA score and vasoactive drugs dosage were collected at PEEP 10. SOFA score and vasoactive drugs dosage were significantly higher in the stable group.