Table 6 Characteristics of the Study Population (mRNA expression study) (n = 55)
From: Selective accumulation of langerhans-type dendritic cells in small airways of patients with COPD
| Â | Never Smokers | Current Smokers without COPD | Ex-Smokers without COPD | COPD Current Smokers | COPD Ex-Smokers |
|---|---|---|---|---|---|
n | 10 | 7 | 10 | 17 | 11 |
Sex ratio (M/F) | 3/7 | 3/4 | 8/2 | 14/3 | 11/0 |
Age (years) | 59.5 (11.2) | 53.1 (13.4) | 63.6 (7.7) | 63.9 (9.5) | 69.3 (7.7) |
Smoking history (packyear) | 0 | 34.8 (12) * | 37.5 (20.6) * | 41.2 (16.9) †| 56.1 (24.1) * |
Years quit smoking | N.A. | 0.0 | 9.0 (10.7) †| 0.0 ‡ | 5.8 (6.0)†Δ |
FEV1 (%pred) | 97.3 (13) | 101.8 (16.7) | 112.2 (10.1) | 68.3 (13.6)*†‡ | 68.8 (14.6)*†‡ |
FEV1 (L) | 2.8 (0.7) | 2.9 (0.4) | 3.4 (0.7) | 2.3 (0.6)‡ | 2.1 (0.5)*†‡ |
FEV1/FVC (%) | 77.2 (8.1) | 77.2 (4.9) | 77.2 (6.1) | 56.1 (7.0)*†‡ | 55.6 (9.2)*†‡ |
LABA (Y/N) | 0/10 | 0/7 | 0/10 | 6/11 | 5/6 |
Inhaled corticosteroids (Y/N) | 0 | 0 | 0 | 6/11 | 5/6 |
Inhaled corticosteroid dose (μg BDP/24 h) | 0 | 0 | 0 | 538.5 (877.1)*†‡ | 663.6 (897.0)*†‡ |
Systemic corticosteroids (Y/N) | 0/10 | 0/7 | 0/10 | 3/14 | 1/10 |
Systemic corticosteroid dose (mg prednisolon/24 h) | 0 | 0 | 0 | 3.1 (10.0) | 0.9 (3.0) |