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Table 1 Patient groups

From: Expression, regulation and clinical significance of soluble and membrane CD14 receptors in pediatric inflammatory lung diseases

 

Pneumonia

Cystic fibrosis

Asthma

Controls

 

bacterial

non-bacterial

   

N

31

17

39

15

8

Age [yrs]

10 ± 5

12 ± 7

11 ± 6

10 ± 4

9 ± 4

Sex (m:f)

19/12

9/8

23/16

7/8

5/3

CRP (mg/l)

114 ± 64

53 ± 25

8 ± 3

12 ± 4

2 ± 1

WBC (109/l)

20 ± 8

11 ± 5

9 ± 4

10 ± 5

8 ± 2

Atopy

4/31

5/17

11/39

15/15

0/8

FEV1 (% pred)

-

-

95 ± 20

68 ± 12

-

FVC (% pred)

-

-

93 ± 19

73 ± 26

-

Bacteria detected

31

0

30/39

3/15

0/8

BALF cells

     

Viability (%)

76 ± 20

70 ± 14

76 ± 34

81 ± 26

85 ± 13

Recovery (%)

62 ± 24

52 ± 18

42 ± 17

56 ± 11

58 ± 18

Total cells (103/ml)

962 ± 303

712 ± 144

3240 ± 9380

240 ± 113

145 ± 23

Neutrophils (%)

38 ± 24

10 ± 13

63 ± 31

16 ± 23

2 ± 1

Macrophages (%)

55 ± 28

62 ± 34

33 ± 16

74 ± 21

87 ± 9

Lymphocytes (%)

12 ± 16

20 ± 11

5 ± 3

13 ± 14

5 ± 3

Eosinophils (%)

4 ± 2

2 ± 3

2 ± 1

5 ± 2

0 ± 0

Mast cells (%)

1 ± 1

1 ± 2

1 ± 1

2 ± 1

0 ± 1

Plasma cells (%)

4 ± 7

8 ± 5

3 ± 4

6 ± 4

2 ± 1

BALF cells analyzed by flow cytometry

15/31

8/17

9/39

13/15

8/8

  1. results are expressed as means ± SD; m: male, f: female; WBC: white blood count; FEV1: Forced expiratory volume in 1 second (% of predicted); FVC: Forced vital capacity (% of predicted); BALF: bronchoalveolar lavage fluid; CRP: C-reactive protein; WBC: white blood cell count; *Pathogens detected in any patients sample at time of study (blood, BALF or sputum).