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Table 2 Results of multiple linear regression analyses for 6 MWD, maximum exercise, quality of life, and shortness of breath.

From: Anxiety is associated with diminished exercise performance and quality of life in severe emphysema: a cross-sectional study

       Model fit
  B SE Beta p 95% Confidence Interval for B R 2 p
6MWD        
   Age (years) -2.37 .37 -.14 <.001 [-3.09, -1.65]   
   Male Gender 45.04 4.78 .21 <.001 [35.67, 54.40]   
   FEV1% 3.39 .33 .25 <.001 [2.75, 4.03]   
   DLCO% 2.61 .23 .25 <.001 [2.15, 3.06]   
   Depression-M .26 .79 .01 .746 [-1.30, 1.81]   
   Depression-P -2.64 .85 -.08 .002 [-4.31, -.97]   
   Anxiety -.99 .24 -.10 <.001 [-1.45, -.52] .22 <.001
Max. exercise        
   Age (years) -.62 .07 -.18 <.001 [-.75, -.49]   
   Male Gender 20.44 .85 .45 <.001 [18.77, 22.11]   
   FEV1% 1.14 .06 .40 <.001 [1.03, 1.26]   
   DLCO% .50 .04 .23 <.001 [.42, .58]   
   Depression-M .21 .14 .03 .142 [-.07, .49]   
   Depression-P -.73 .15 -.11 <.001 [-1.02, -.43]   
   Anxiety -.10 .04 -.05 .017 [-.19, -.02] .43 <.001
Quality of life        
   Age (years) -.26 .04 -.13 <.001 [-.35, -.18]   
   Male Gender 1.18 .56 .04 .037 [.07, 2.29]   
   FEV1% -.10 .04 -.06 .012 [-.17, -.02]   
   DLCO% -.07 .03 -.05 .018 [.-12, -.01]   
   Depression-M .31 .09 .09 .001 [.12, .49]   
   Depression-P 1.34 .10 .33 <.001 [1.15, 1.54]   
   Anxiety .187 .03 .16 <.001 [.13, .24] .28 <.001
Shortness of Breath        
   Age (years) -.132 .07 -.04 .045 [-.26, -.01]   
   Male Gender -2.940 .85 -.07 .001 [-4.61, -1.27]   
   FEV1% -.345 .06 -.14 <.001 [-.46, -.23]   
   DLCO% -.285 .04 -.15 <.001 [-.37, -.20]   
   Depression-M .139 .14 .03 .331 [-.14, .42]   
   Depression-P 1.836 .15 .30 <.001 [1.54, 2.13]   
   Anxiety .206 .04 .12 <.001 [.12, .29] .24 <.001
  1. Unstandardized regression coefficients (B), standard errors (SE), standardized coefficients (Beta), significance values (p), and 95% confidence intervals are shown for each independent variable. Goodness-of-fit (R2) shown for each regression model. For each regression model, BDI depression was entered either as total score or as two separate independent variables composed of the mood (Depression-M) or physical (Depression-P) BDI symptom items.
  2. FEV1%: forced expiratory volume in 1 second, percent of predicted.
  3. DLCO%: single-breath diffusing capacity of carbon monoxide, percent of predicted.