Table 2 Analysis of IL-6 in the relationship between disease status and lung function
Simple Regression Analyses | Â | Â |
|---|---|---|
Path X | Â | Â |
Disease status (asthma) | IL-6 (mediator) 10.68a (2.86)b p < 0.0007 | Â |
Path Y | Â | Â |
| Â | Lung function Parameters | |
IL-6 (mediator) | FEV1/FVC% predicted | PEFR |
| Â | -0.5 (0.16) p = 0.0025 | -0.45 (0.16) p = 0.0088 |
Path Z | Â | Â |
| Â | Lung function Parameters | |
Disease status (asthma) | FEV1/FVC% predicted | PEFR |
| Â | -13.58 (2.51) p < 0.0001 | -9.21 (3.07) p = 0.0052 |
Multiple Regression Analyses | Â | Â |
| Â | Lung function Parameters | |
| Â | FEV1/FVC% predicted | PEFR |
Disease status (asthma) | -11.69 (2.99) p = 0.0005 | -6.34 (3.62) p = 0.09 |
IL-6 (mediator) | -0.177 (0.15) p = 0.2594 | -0.27 (0.19) p = 0.1599 |