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Table 2 Analysis of IL-6 in the relationship between disease status and lung function

From: Elevation of IL-6 in the allergic asthmatic airway is independent of inflammation but associates with loss of central airway function

Simple Regression Analyses   
Path X   
Disease status (asthma) IL-6 (mediator)
10.68a (2.86)b
p < 0.0007
 
Path Y   
  Lung function Parameters
IL-6 (mediator) FEV1/FVC% predicted PEFR
  -0.5 (0.16)
p = 0.0025
-0.45 (0.16)
p = 0.0088
Path Z   
  Lung function Parameters
Disease status (asthma) FEV1/FVC% predicted PEFR
  -13.58 (2.51)
p < 0.0001
-9.21 (3.07)
p = 0.0052
Multiple Regression Analyses   
  Lung function Parameters
  FEV1/FVC% predicted PEFR
Disease status (asthma) -11.69 (2.99)
p = 0.0005
-6.34 (3.62)
p = 0.09
IL-6 (mediator) -0.177 (0.15)
p = 0.2594
-0.27 (0.19)
p = 0.1599
  1. a: β-coefficient
  2. b: standard errors