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Table 1 Patient Demographics

From: Elevation of IL-6 in the allergic asthmatic airway is independent of inflammation but associates with loss of central airway function

Criteria Control Subjects Mild to Moderate Asthmatic Subjects
Number 16 18
Sex (M/F) 6/10 7/11
Age, yr 25.2 ± 6.0 25.9 ± 9.4
Antileukotrienes 0 2
Inhaled Steriods 0 9
FEV1 % predicted 105.6 ± 11.4 90.2 ± 14.3
FEV1/FVC % predicted 101.5 ± 4.1 87.6 ± 9.8§
PC20 (mg/ml) >16 1.0 (0.48-2.1)
Squamous cells (%) 1.5 (3.8)* 2.0 (6.0)*
Lung Epithelial cells (%) 2.0 (5.3)* 2.5 (3.0)*
Eosinophils (%) 1.1 (3.0)* 2.0 (6.0)*
Neutrophils (%) 19.85 (21.1)* 6.95 (17.8)*
  1. Values are reported as means ± SD unless otherwise indicated. Definition of abbreviations: F = females, FEV1 = forced expiratory volume in 1 second, FEV1/FVC = FEV1/forced vital capacity, M = males, PC20 = provocation concentration of methacholine causing a 20% fall in FEV1. The percentage of eosinophils and neutrophils are reported for induced sputum.
  2. Geometric mean (range)
  3. *Median (interquartile range)
  4. p = 0.004, asthmatic vs. control group
  5. §p < 0.0001, asthmatic vs. control group