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Table 4 Pharmacokinetic Analysis for GSK256066.

From: The inhaled phosphodiesterase 4 inhibitor GSK256066 reduces allergen challenge responses in asthma

Parameter unit Day 1 Day 7
AUC (0-t) pg.h./mL 36.8 (93) 64.8 (89)
Cmax Pg/mL 18.3 (68) 17.3 (63)
Tmax h 1.0 (0.17-3.00) 1.0 (0.17-11.0)
Tlast h 3.0 (0.5-6.0) 4.0 (1.0-24)
  1. Values are geometric means (CV%) for AUC(0-t) and Cmax, and medians (range) for Tmax and Tlast. 0-t = From 0 hrs to time of last measurable concentration. N = 18 on Day 1, and n = 17 on Day 7.